Diinodlylmethane ? Cruciferous Patented DIM. Estrogen Metabolism Formula ? Promotes healthy estrogen metabolism.Enhanced Absorption Patentedwith Protectamins Vegetable Blend. DIM-plus contains diindolylmethane, a phytonutrient found in cruciferous vegetables including broccoli, brussels sprouts, cabbage, cauliflower and kale. Unlike other plant nutrients such as soy isoflavones, diindolylmethanehas unique hormonal benefits. It supports the activity of enzymes that improve estrogen metabolism. Scientific research shows diindolylmethane increases the level of "good" estrogens (2-hydroxyestrogen) while reducing the level of "bad" estrogens (16-hydroxyestrogen).