A Gradual Hormonal Decline Between age 40 and 55, men can experience a phenomenon similar to the female menopause, called Andropause. Similar to women's drop in estrogen levels, men experience a shift in hormone levels, most notably their testosterone. However, these changes occur very gradually in men and often come with changes in physical performance and appearance, moods, fatigue, loss of energy, sex drive and even general health concerns such as prostate enlargement and cardiovascular disease. Despite knowing that a decline in testosterone levels will occur in nearly all men, there are no significant indicators for predicting who will experience Andropausal symptoms of particular severity to require medical assistance or at what age these symptoms will occur.The Male Version Of Menopause Originally, Andropause was believed to be treated through the enhancement of testosterone, as it is closely related to a man's masculinity, virility and sexuality. However, physicians soon discovered that testosterone enhancement alone was not the answer.The male endocrine system is very complex. In order to achieve proper hormone homeostasis (balance) the following must be addressed: Testosterone, Luteinizing hormone (LH), Sex Hormone Binding Globulin (SHBG), Estrogen and Dihydrotestosterone (DHT).